Primary proliferative response of naive autologous CD4⁺ and CD8⁺ T cells upon stimulation by DCs expressing HCV F and core antigens.

<p>Purified CD4⁺ and CD8⁺ T cells were stimulated using DCs expressing HCV antigens at various DC:T cell ratios. The proliferation of T cells was determined by a ³H-thymidine incorporation assay. The lines on the graphs represent DCs with no antigens, DCs expressing control vector, core protein, and F protein according to the figure legends. Mean and standard deviations of triplicate wells are shown. The data are representative of 5 repeated experiments with 5 different donors.