PBA treatment inhibited ER stress and ameliorated atherosclerosis <i>in vivo</i>.

<p><b>A.</b> Protein was obtained from the thoracic and abdominal aorta of ApoE^−/− mice with or without PBA treatment and the expressions of phosphorylated eIF-2α (p-eIF2α), total eIF-2α, spliced XBP-1 (sXBP-1) and β-actin were detected by Western Blot. (n = 2 per group) <b>B.</b> The aortic root sections were stained by rabbit anti- phosphorylated-PERK (p-PERK) and expression of p-PERK in plaque was analyzed by immunohistochemistry. (n = 10 per group), *p<0.05, ***p<0.001.