Neutralization of HIV-1 pseudovirus by Fab and IgG 2F5 and 4E10.

<p>The fraction neutralized is plotted against the concentration of Fab sites. The inserts in A, B and C are the calculated values of from <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003431#pcbi.1003431.e136" target="_blank">Eq. (7)</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003431#pcbi.1003431.e162" target="_blank">(10)</a> versus the concentration of Fab sites for and the parameters given in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003431#pcbi-1003431-t002" target="_blank">Table 2</a>. Neutralization by A. 2F5 Fab (red circles) and two preparations of 2F5 IgG (solid squares and open circles), B. 4E10 Fab (blue squares) and 4E10 IgG (green circles), and C. 2F5 IgG from panel A and 4E10 IgG from panel B.