Quantification of increase of polyribosomes in myelinated axons in the phrenic nerve of SOD1^G93A mutant mice.

<p>Both the percentage of myelinated axons containing ribosomes (A) as well as the absolute number of ribosomes in axons (B) has increased dramatically in both presymptomatic (12 weeks PN, n = 5, *p<0.01) as well as symptomatic (17 weeks PN n = 5, *p<0.01) compared to their littermate controls (Ntg, n = 5) and SOD1 Wt animals, (n = 5) whereas there are no statistical differences between the presymptomatic and symptomatic groups.