NK-cells from IFN-OFF patients have a mature phenotype.

<p>NK-cell proportions and surface markers CD62L, CD57 and CD27 were analyzed with flow cytometry and absolute NK-cell counts were counted from total lymphocyte numbers. <b>A)</b> The proportion of NK-cells in IFN-OFF and IFN-ON patients <b>B)</b> Absolute amount of NK-cells in IFN-ON and IFN-OFF patients <b>C)</b> The proportion of CD56^DIM NK-cells from CD56 NK-cells in IFN-ON and IFN-OFF patients <b>D)</b> Absolute amounts of CD56^DIM NK-cells in IFN-ON and IFN-OFF patients. <b>E)</b> CD57 expression in CD56^DIM NK-cells. <b>F)</b> CD62L expression in CD56^DIM NK-cells <b>G)</b> CD27 expression in CD56^DIM NK-cells. White dots represent pregnant patients in IFN-ON group (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0087794#pone-0087794-t001" target="_blank">Table 1</a>).