Lung histopathology in drug-treated and untreated infected mice.

<p>(A) Images are shown for TB-infected Balb/c mice treated with 80% aqueous propylene glycol (mock), ND-09759 alone, ND-09759 plus INH or RMP, or with INH or RMP alone. The left and right panels show low power (original magnification 50X) and high power (original magnification 400X) of H&E-stained lung sections, respectively. Sections are representative of lung sections from 5 mice per group and from one of two independent experiments. (B) Quantitative scoring of histopathology. Bars represent means ±standard deviation.