Glia mediates the effect of HMGB-1.

<p>(<b>A</b>) Primary pericytes co-cultured with glia were treated with HMGB-1 (5 µg/mL, 24 hours). Pericyte survival was assessed using an apoptosis assay kit. All experiments were repeated at least three times (**P<0.01). (<b>B</b>) Representative confocal images.