Principal component analysis of the motif representation data of HIV-1 sequences from subtypes/recombinant B, C, A1 and 01_AE.

<p>a) Scores plot (PC11 vs. PC13). Each point is an HIV-1 full genome sequence. The accession numbers of the two sequences that extend in the direction of mutation by APOBEC3F and/or other similar APOBEC3 members are shown near their points. b) Loadings plot (PC11 vs. PC13). Each point is a motif. The arrow shows the direction of GA→AA mutation by APOBEC3F and/or other similar APOBEC3 enzymes.