Effects of HSA mutation on the intensity of induced CD of curcuminoids-HSA systems at pH 9.0.

<p>The binding of curcuminoids (25 µM) to WT-HSA and HSA mutants (50 µM) in Tris-HCl buffer (pH 9.0 and 25°C) was studied by CD measurement. Results are the means ± SD of triplicate experiments. *, **, ***P< 0.05 versus native HSA.