<p>Following injections of scAAV2-GFP into the DRG and BDA into the sensorimotor cortex, sections of cervical spinal cord were examined in normal (A–D) and dorsal column lesion animals (E–L). GFAP staining labeling the lesion cavity are shown in blue (G and K). scAAV2-GFP-labeled dorsal sensory axons are shown in green (right of the lesion) (E and I) and BDA labeled CST fibers are shown in red (left of the lesion) (F and J). Scale Bars: 500 µm (A–H), 200 µm (I–L).</p
<p>Animals received a dorsal column transection or a sham lesion at T7 or C4 level and survived eigh...
<p><b><i>A</i></b><i>:</i> Schematic of labelling protocol and areas of interest. <b><i>B</i></b>: L...
Achieving axon regeneration after nervous system injury is a challenging task. As different parts of...
<p>Dorsal column lesion resulted in a corresponding loss of CST axons, as visualized by anterograde ...
<p>GFP-labeled axons were examined after dorsal root crush injury. In un-injured animals, GFP-labele...
<p>GFP expressed in DRG neurons of the cervical spinal cord after scAAV2-GFP intraganglion injection...
Various types of tracers are available for use in axon regeneration, but they require an extra opera...
<p>(<b>A–L</b>) Images of the BDA-labeled CST at 5, 9 and 11 mm rostral to the lesion are depicted i...
<p>A shows the bright field of low-power image of sensorimotor cortex and corresponding low-power an...
The histological assessment of spinal cord tissue in three dimensions has previously been very time ...
<p><b>A</b>. Hindlimb CST axons were labeled by injecting biotinylated dextran amine (BDA) into 9 si...
<div><p>Panels (A), (B), and (C): Texas red-dextran amine labeling of corticospinal fibers. Texas re...
<p>Coronal spinal cord sections were analyzed in the parenchyma and around the central canal. (A) Qu...
<p><b>ABC</b>) ChAT staining of transverse sections of a non-avulsed sciatic nerve (a) shows thick m...
<p>ΔfosB staining was used to measure the extent of persistent neuronal activation in the spinal cor...
<p>Animals received a dorsal column transection or a sham lesion at T7 or C4 level and survived eigh...
<p><b><i>A</i></b><i>:</i> Schematic of labelling protocol and areas of interest. <b><i>B</i></b>: L...
Achieving axon regeneration after nervous system injury is a challenging task. As different parts of...
<p>Dorsal column lesion resulted in a corresponding loss of CST axons, as visualized by anterograde ...
<p>GFP-labeled axons were examined after dorsal root crush injury. In un-injured animals, GFP-labele...
<p>GFP expressed in DRG neurons of the cervical spinal cord after scAAV2-GFP intraganglion injection...
Various types of tracers are available for use in axon regeneration, but they require an extra opera...
<p>(<b>A–L</b>) Images of the BDA-labeled CST at 5, 9 and 11 mm rostral to the lesion are depicted i...
<p>A shows the bright field of low-power image of sensorimotor cortex and corresponding low-power an...
The histological assessment of spinal cord tissue in three dimensions has previously been very time ...
<p><b>A</b>. Hindlimb CST axons were labeled by injecting biotinylated dextran amine (BDA) into 9 si...
<div><p>Panels (A), (B), and (C): Texas red-dextran amine labeling of corticospinal fibers. Texas re...
<p>Coronal spinal cord sections were analyzed in the parenchyma and around the central canal. (A) Qu...
<p><b>ABC</b>) ChAT staining of transverse sections of a non-avulsed sciatic nerve (a) shows thick m...
<p>ΔfosB staining was used to measure the extent of persistent neuronal activation in the spinal cor...
<p>Animals received a dorsal column transection or a sham lesion at T7 or C4 level and survived eigh...
<p><b><i>A</i></b><i>:</i> Schematic of labelling protocol and areas of interest. <b><i>B</i></b>: L...
Achieving axon regeneration after nervous system injury is a challenging task. As different parts of...