Basal cell (BC) smoking-dysregulated genes localized to COPD-risk locus 19q13.2.

<p><b>A.</b> Genome distribution of 13 significant BC smoking-dysregulated genes on locus 19q13.2. Red bar – known COPD locus; red dots – known COPD candidate genes (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0088051#pone.0088051.s001" target="_blank">Table S1 in File S1</a>). <b>B.</b> Expression of BC smoking-dysregulated genes on 19q13.2. Expression is in fragments per kilobase of exon per million fragments mapped (FPKM). Nonsmoker (n = 10, green bars), smoker (n = 7, yellow bars). All smoker to nonsmoker comparisons minimum p<0.05. The 4 COPD risk genes are in red.