<p>A. Incidence of spontaneous EAE in a cohort of RR SJL/J (n = 14) or RR B10.S mice (n = 17). B. Frequencies of CD3<sup>+</sup> CD4<sup>+</sup> T cells in spleen, pooled axillary and inguinal lymph nodes (pLN), mesenteric lymph nodes (mLN), Peyer's patches (PP) and small intestinal lamina propria (siLP) were measured by flow cytometry. C. Frequencies of Foxp3<sup>+</sup> CD3<sup>+</sup> CD4<sup>+</sup> regulatory T cells in the indicated organs were measured by flow cytomtery. Results are from n = 4–6 mice per group. Data were pooled from 2–3 different experiments (B–C). Error bars indicate SEM (B–C).</p
<p><b>A)</b> Total splenocyte numbers were determined. Lines indicate the mean, and each symbol repr...
<p>(<b>A</b>) EAE was induced in <i>pik3cg<sup>−/−</sup></i> (n = 21) and WT (n = 19) mice. Clinical...
<p>(A) EAE was induced in mice by immunization with MOG<sub>35-55</sub> peptide, using either 50 μg ...
<p>Flow cytometry showing the percentages (A, B) and absolute numbers (C) of CD4<sup>+</sup>CD25<sup...
<p>A) Flow cytometry of small intestinal intraepithelial cells isolated from 2 weeks old dam fed wil...
<p>(A-B) Both MBP TCR Tg B10.PL mice and CD2-SRG3/MBP TCR double Tg B10.PL mice (upper panel) or bot...
Plots are gated on CD3 cells (A) or GFP CD3 cells (B). Numbers indicate mean percent cells in quadra...
<p>A. Example of analysis of splenocytes from a C57BL/6 mouse transduced with AAV-LacZ and, 6 weeks ...
<p>(A) Representative thymi dissected from <i>spc/spc</i> and WT (+/+) littermate mice at 4 weeks of...
<p>(a), Splenocytes were stained with FITC-CD4 and PE-FoxP3 antibody, the frequencies of Treg cells ...
<p>A-D) Splenocytes or mucosal lymphocytes harvested from untreated Egr3WT or Egr3TG mice were count...
<p>Mice were i.c. infected and analyzed at 3, 7, 10, 14, and 28 dpi as indicated. The percentages of...
(A) Representative flow cytometry analysis of CD4+ Foxp3+ cells among CD3+ cells from spleen, lung, ...
<p>Induction of EAE was attempted in WT, cathepsin B (Cat B<sup>-/-</sup>), cathepsin S (Cat S<sup>-...
<p>Splenocytes and lysed blood cells were stained with respective antibodies and subjected to flow c...
<p><b>A)</b> Total splenocyte numbers were determined. Lines indicate the mean, and each symbol repr...
<p>(<b>A</b>) EAE was induced in <i>pik3cg<sup>−/−</sup></i> (n = 21) and WT (n = 19) mice. Clinical...
<p>(A) EAE was induced in mice by immunization with MOG<sub>35-55</sub> peptide, using either 50 μg ...
<p>Flow cytometry showing the percentages (A, B) and absolute numbers (C) of CD4<sup>+</sup>CD25<sup...
<p>A) Flow cytometry of small intestinal intraepithelial cells isolated from 2 weeks old dam fed wil...
<p>(A-B) Both MBP TCR Tg B10.PL mice and CD2-SRG3/MBP TCR double Tg B10.PL mice (upper panel) or bot...
Plots are gated on CD3 cells (A) or GFP CD3 cells (B). Numbers indicate mean percent cells in quadra...
<p>A. Example of analysis of splenocytes from a C57BL/6 mouse transduced with AAV-LacZ and, 6 weeks ...
<p>(A) Representative thymi dissected from <i>spc/spc</i> and WT (+/+) littermate mice at 4 weeks of...
<p>(a), Splenocytes were stained with FITC-CD4 and PE-FoxP3 antibody, the frequencies of Treg cells ...
<p>A-D) Splenocytes or mucosal lymphocytes harvested from untreated Egr3WT or Egr3TG mice were count...
<p>Mice were i.c. infected and analyzed at 3, 7, 10, 14, and 28 dpi as indicated. The percentages of...
(A) Representative flow cytometry analysis of CD4+ Foxp3+ cells among CD3+ cells from spleen, lung, ...
<p>Induction of EAE was attempted in WT, cathepsin B (Cat B<sup>-/-</sup>), cathepsin S (Cat S<sup>-...
<p>Splenocytes and lysed blood cells were stained with respective antibodies and subjected to flow c...
<p><b>A)</b> Total splenocyte numbers were determined. Lines indicate the mean, and each symbol repr...
<p>(<b>A</b>) EAE was induced in <i>pik3cg<sup>−/−</sup></i> (n = 21) and WT (n = 19) mice. Clinical...
<p>(A) EAE was induced in mice by immunization with MOG<sub>35-55</sub> peptide, using either 50 μg ...