Effects of PTH on the expression of angiogenic and neurotrophic factors.

<p>The expression of key pro-regenerative factors in the peri-infarct region was detected using Western blot analysis. <b>A</b>. Electrophoresis gels show the protein levels of VEGF, BDNF, EPOR, SDF-1, and Tie-1 in the ischemic peri-infarct region in different animals 6 days after stroke. <b>B</b> to <b>F</b>. Densitometry analysis of the expression of BDNF (B), VEGF (C), EPOR (D), SDF-1 (E), and Tie-1 (F). Gray intensity was normalized against β-actin and quantified. PTH treatment significantly enhanced the expression of all these factors shown in A, compared with the stroke-saline group. N = 3 animals for each test; * <i>P</i><0.05.