Effect of lithium (Li) on glial differentiation of BrdU(+) cells generated following neuronal loss.

<p>Animals were given either lithium carbonate (100 mg/kg, i.p.) or PBS with BrdU on day 2 post-treatment with PBS or TMT, subsequently given once a day either lithium carbonate or PBS up to day 15, and then decapitated on day 30 post-treatment for preparation of sagittal hippocampal sections, which were then stained with antibodies against GFAP or Iba1 and BrdU (Schedule 3). The graphs denote the number of double-positive cells in the GCL+SGZ of the 4 groups. Values are expressed as the mean ± S.E. calculated from 4 animals.