<p>A549 cells transfected with 100(A, B). A549 cells transfected with Chk1 siRNA and treated with or without 200 nM Cuc B for 24 h. Phosphorylation of Cdc25C on Ser-216, Cdk1 on were analyzed by Western blot (C). <sup>*</sup><i>p</i><0.05 <i>vs.</i> Cont. Cont, control group.</p
<p>(A) Cyclin B (Cdc13) was immunoprecipitated from untreated and CPT-treated (40μM CPT, 4h) <i>cdc1...
<p>(A) lysates from MDA-MB-231 wt, SK-1 kd, and SK-1 overexpressing cells (SK-1 ov) were subjected t...
<p>(<b>A</b>) Reduced level of IκBα after CHC knockdown in HeLa cells. Cell lysates from control or ...
<p>The generation of ROS in A549 cells after 50, 100, 200<sub>2</sub>-DA as described under Material...
<p>Cuc B induced ROS formation, which lead to DNA damage. In response to DNA damage, ATM <i>via</i> ...
<p>Cell cycle analysis was performed by flow cytometry. Representative cell cycle profiles of A549 c...
<p>(A) MEF<sup><i>Ctl</i>.</sup> cells were transfected with control siRNA (siNeg) or siRNA targetin...
<p><b>A</b>. Double thymidine block experiments were performed in HEY cells treated with DMSO contro...
<p>(A) Western blot analysis of the activation of p53, MDM2, Chk1 and Chk2 in Huh7 and PLC/PFR/5 cel...
<p>UMUC-3, TCCSUP and RT112 cells were transfected with cdk2 or cyclin A siRNA and knock down was co...
<p><i>(A) Reversal of S-phase accumulation following Chk2 inhibition.</i> FACS analysis was carried ...
Checkpoint kinase 1 (Chk1) is a checkpoint gene that is activated after DNA damage. It phosphorylate...
<p>A549 cells were untreated or treated with LBH589 (40 nM) for various time points. Cell lysates we...
<p><i>(A) siRNA depletion of Chk2 reduces MVM replication.</i> A9 cells were transfected twice with ...
Checkpoint kinase 1 (CHK1) is a key mediator that links the machineries that monitor DNA integrity t...
<p>(A) Cyclin B (Cdc13) was immunoprecipitated from untreated and CPT-treated (40μM CPT, 4h) <i>cdc1...
<p>(A) lysates from MDA-MB-231 wt, SK-1 kd, and SK-1 overexpressing cells (SK-1 ov) were subjected t...
<p>(<b>A</b>) Reduced level of IκBα after CHC knockdown in HeLa cells. Cell lysates from control or ...
<p>The generation of ROS in A549 cells after 50, 100, 200<sub>2</sub>-DA as described under Material...
<p>Cuc B induced ROS formation, which lead to DNA damage. In response to DNA damage, ATM <i>via</i> ...
<p>Cell cycle analysis was performed by flow cytometry. Representative cell cycle profiles of A549 c...
<p>(A) MEF<sup><i>Ctl</i>.</sup> cells were transfected with control siRNA (siNeg) or siRNA targetin...
<p><b>A</b>. Double thymidine block experiments were performed in HEY cells treated with DMSO contro...
<p>(A) Western blot analysis of the activation of p53, MDM2, Chk1 and Chk2 in Huh7 and PLC/PFR/5 cel...
<p>UMUC-3, TCCSUP and RT112 cells were transfected with cdk2 or cyclin A siRNA and knock down was co...
<p><i>(A) Reversal of S-phase accumulation following Chk2 inhibition.</i> FACS analysis was carried ...
Checkpoint kinase 1 (Chk1) is a checkpoint gene that is activated after DNA damage. It phosphorylate...
<p>A549 cells were untreated or treated with LBH589 (40 nM) for various time points. Cell lysates we...
<p><i>(A) siRNA depletion of Chk2 reduces MVM replication.</i> A9 cells were transfected twice with ...
Checkpoint kinase 1 (CHK1) is a key mediator that links the machineries that monitor DNA integrity t...
<p>(A) Cyclin B (Cdc13) was immunoprecipitated from untreated and CPT-treated (40μM CPT, 4h) <i>cdc1...
<p>(A) lysates from MDA-MB-231 wt, SK-1 kd, and SK-1 overexpressing cells (SK-1 ov) were subjected t...
<p>(<b>A</b>) Reduced level of IκBα after CHC knockdown in HeLa cells. Cell lysates from control or ...