Immunofluorescence staining of DNA double strand breaks (γH2AX) in AR42J tumors after treatment with 47 kBq <sup>225</sup>Ac-DOTATOC, 30 MBq of <sup>177</sup>Lu-DOTATOC, 1 µg DOTATOC (unlabelled), or PBS.
- Franziska Graf (582705)
- Jörg Fahrer (454565)
- Stephan Maus (582706)
- Alfred Morgenstern (372625)
- Frank Bruchertseifer (372624)
- Senthil Venkatachalam (582707)
- Christian Fottner (582708)
- Matthias M. Weber (582709)
- Johannes Huelsenbeck (201895)
- Mathias Schreckenberger (582710)
- Bernd Kaina (22761)
- Matthias Miederer (372618)
Publication date
February 2014
DOIAbstract
<p>(<b>A</b>) Representative images, (B) and quantification of γH2AX- positive cells. Scale bar (white) corresponds to 25 µm. (C) Growth delay after treatment with equitoxic doses of <sup>225</sup>Ac-DOTATOC (n = 3, 44kBq/mouse) and <sup>177</sup>Lu-DOTATOC (n = 4, 34 MBq/mouse) versus untreated control (n = 4).</p
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