Demographics of study subjects according to their drug using status.

<p>a. Diagnosed type 2 diabetes mellitus (T2DM) patients who did not use statin before the end of follow up date.</p><p>b. The statin regular user is the patient who uses statin continuously at least over one year in the follow up time that nearby 2 statin prescriptions can't exceed 120 days.</p><p>This group of diagnosed T2DM patients is statin regular user group.</p><p>c. Wilcoxon rank sum test or Pearson's Chi-square test.</p><p>d. The case number is calculated before patient's index date.</p><p>The index date of patient who never uses statin before the end of follow up date is the T2DM diagnosed date.</p><p>The index date of patient who is statin regular user is the date of staring to take statin regularly.</p><p>e. The case number is the regular use of statin after patient's T2DM diagnosed date.</p><p>f. The case number is the regular use of the anti-diabetic drug before patient's index date.</p><p>g. Charlson comorbidity index (CCI): The diagnoses recorded in the National Health Insurance Research Database before the index date is used to calculate CCI score.</p><p>We exclude the diagnosis of diabetes mellitus and stroke from CCI score calculation, because these two disease entities are considered separately.