E-selectin expression is upregulated in the presence of peripheral serotonin.

<p>Immunofluorescence for E-selectin (red) and nuclei (blue). Mesenteric venules at baseline conditions (A), after fluoxetine treatment (B), after serotonin challenge (C) and after lipopolysaccharide stimulation (D) of WT mice. Mesenteric venules of Tph1−/− mice at baseline (E), after fluoxetine treatment (F), after serotonin challenge (G) and after lipopolysaccharide stimulation (H). Semi quantification of fluorescence-levels for E-selectin (I). Scale bar = 50 µm; Flx = fluoxetine, LPS = lipopolysaccharide. ** = p<0.001.