<p>C57BL/6 diet induced obesity mice were treated twice weekly with either control antibody (10 mg/kg) or XMetS (10 mg/kg). Age-matched, lean C57BL/6 mice were treated twice weekly with control antibody (10 mg/kg). After one week of treatment and following a 14-hour overnight fast, a glucose bolus was administered intraperitoneally (1 g/kg) and blood glucose levels were measured for 120 minutes. Mean ± SEM are shown (n = 10 mice/group).</p
<p>A: Oral glucose tolerance test was performed on db/db mice (n = 4) treated with different treatme...
<p>Mice were provided ad libitum access to high fat diet (HFD) lacking or containing 0.14% ursolic a...
<p>(A) The intraperitoneal injections of GLP-1/<i>h</i>IgG2 (1 µg/mouse) were made every three days ...
<p><b>A–C.</b> ICR multi-low dose, streptozotocin/high-fat diet mice were treated twice weekly with ...
<p>At the end of the 4-week study with diet induced obesity mice, the animals were fasted 14 hours, ...
<p>At the end of the 6-week study with multi-low dose, streptozotocin/high-fat diet mice, the animal...
<p>(a) Phosphorylation of AMPK and ACC in the skeletal muscle of high-fat diet-induced diabetic mice...
Previously we reported studies of XMetA, an agonist antibody to the insulin receptor (INSR). We have...
<p>Male TSP1-/- mice and wild type littermate controls were fed LF or HF diet for 16 weeks. Intraper...
<p>(A) Blood glucose levels were measured in overnight-fasted female <i>db/db</i> mice (n = 9–10 per...
<p>The WT and <i>db/db</i> mice were fed a standard laboratory diet for 9 weeks. Body weight and the...
<p>Overnight-fasted C57BL/6 mice were orally dosed with vehicle (white circles), sitagliptin (sita) ...
<p>Mice were fed a LFD or HFD for 5 months and then treated with MnTBAP (10 mg/kg) alone or in combi...
<div><p>(A) Eleven-week-old wild-type C57B6 mice were fed a high-fat diet in combination with vehicl...
Decreased metabolic flexibility, i.e. a compromised ability to adjust fuel oxidation to fuel availab...
<p>A: Oral glucose tolerance test was performed on db/db mice (n = 4) treated with different treatme...
<p>Mice were provided ad libitum access to high fat diet (HFD) lacking or containing 0.14% ursolic a...
<p>(A) The intraperitoneal injections of GLP-1/<i>h</i>IgG2 (1 µg/mouse) were made every three days ...
<p><b>A–C.</b> ICR multi-low dose, streptozotocin/high-fat diet mice were treated twice weekly with ...
<p>At the end of the 4-week study with diet induced obesity mice, the animals were fasted 14 hours, ...
<p>At the end of the 6-week study with multi-low dose, streptozotocin/high-fat diet mice, the animal...
<p>(a) Phosphorylation of AMPK and ACC in the skeletal muscle of high-fat diet-induced diabetic mice...
Previously we reported studies of XMetA, an agonist antibody to the insulin receptor (INSR). We have...
<p>Male TSP1-/- mice and wild type littermate controls were fed LF or HF diet for 16 weeks. Intraper...
<p>(A) Blood glucose levels were measured in overnight-fasted female <i>db/db</i> mice (n = 9–10 per...
<p>The WT and <i>db/db</i> mice were fed a standard laboratory diet for 9 weeks. Body weight and the...
<p>Overnight-fasted C57BL/6 mice were orally dosed with vehicle (white circles), sitagliptin (sita) ...
<p>Mice were fed a LFD or HFD for 5 months and then treated with MnTBAP (10 mg/kg) alone or in combi...
<div><p>(A) Eleven-week-old wild-type C57B6 mice were fed a high-fat diet in combination with vehicl...
Decreased metabolic flexibility, i.e. a compromised ability to adjust fuel oxidation to fuel availab...
<p>A: Oral glucose tolerance test was performed on db/db mice (n = 4) treated with different treatme...
<p>Mice were provided ad libitum access to high fat diet (HFD) lacking or containing 0.14% ursolic a...
<p>(A) The intraperitoneal injections of GLP-1/<i>h</i>IgG2 (1 µg/mouse) were made every three days ...