<p><b>A, C</b>: The function of aNogo66 mAb or aNogoA-N mAb on branch formation against NogoA was assessed by immunofluorescence. The arrowheads indicate the axon branch points (n = 6 wells per condition; scale bars = 50 µm). <b>B</b>: For statistical analysis, the number of axon branch points per neuron is represented as the mean ± SEM from one representative experiment (<sup>*</sup><i>P</i><0.05, b group vs. a group; <sup>**</sup><i>P</i><0.01, d group vs. c group). <b>D</b>: For statistical analysis, the distance that axons sent out their first branches from the cell body was expressed as the mean ± SEM from one representative experiment (<sup>**</sup><i>P</i><0.01, b group vs. a group; d group vs. c group).</p
Lesioned axons do not regenerate in the adult mammalian central nervous system, owing to the overexp...
AbstractGrowth inhibition in the central nervous system (CNS) is a major barrier to axon regeneratio...
<p>Behavioral studies (Pinprick test) showing the effects of GD1a/GT1b-2b mAb and sham Abs on sensor...
<p><b>A</b>: Dissociated rat E18.5 hippocampal neurons were cultured on the control substrate PLL (c...
<div><p>In a previous study, we generated two monoclonal antibodies (mAbs) in mice, aNogoA-N and aNo...
In a previous study, we generated two monoclonal antibodies (mAbs) in mice, aNogoA-N and aNogo-66 mA...
Myelin-associated axon growth inhibitors such as Nogo and myelin-associated glycoprotein (MAG) play ...
<p>Relative to PBS (A), the number of myelinated axons was significantly increased in mice treated w...
Adult mammalian central nervous system (CNS) axons have very limited capacity of regrowth after inju...
<p>Confocal images of stage 3 hippocampal neurons co-transfected with the Venus plasmid (green) and ...
The use of a monoclonal antibody to block the neurite outgrowth inhibitor Nogo-A has been of great i...
<p>(A, B) High-magnification views of a myelinating oligodendrocyte (A) with MBP (green) expressed i...
Axonal damage leads to permanent deficits in the adult central nervous system (CNS) not only because...
<p>(A-D) Representative images of axons in the axonal compartment stained against neurofilaments (NF...
Amyotrophic Lateral Sclerosis is a devastating neurodegenerative disease that affects motor neurons....
Lesioned axons do not regenerate in the adult mammalian central nervous system, owing to the overexp...
AbstractGrowth inhibition in the central nervous system (CNS) is a major barrier to axon regeneratio...
<p>Behavioral studies (Pinprick test) showing the effects of GD1a/GT1b-2b mAb and sham Abs on sensor...
<p><b>A</b>: Dissociated rat E18.5 hippocampal neurons were cultured on the control substrate PLL (c...
<div><p>In a previous study, we generated two monoclonal antibodies (mAbs) in mice, aNogoA-N and aNo...
In a previous study, we generated two monoclonal antibodies (mAbs) in mice, aNogoA-N and aNogo-66 mA...
Myelin-associated axon growth inhibitors such as Nogo and myelin-associated glycoprotein (MAG) play ...
<p>Relative to PBS (A), the number of myelinated axons was significantly increased in mice treated w...
Adult mammalian central nervous system (CNS) axons have very limited capacity of regrowth after inju...
<p>Confocal images of stage 3 hippocampal neurons co-transfected with the Venus plasmid (green) and ...
The use of a monoclonal antibody to block the neurite outgrowth inhibitor Nogo-A has been of great i...
<p>(A, B) High-magnification views of a myelinating oligodendrocyte (A) with MBP (green) expressed i...
Axonal damage leads to permanent deficits in the adult central nervous system (CNS) not only because...
<p>(A-D) Representative images of axons in the axonal compartment stained against neurofilaments (NF...
Amyotrophic Lateral Sclerosis is a devastating neurodegenerative disease that affects motor neurons....
Lesioned axons do not regenerate in the adult mammalian central nervous system, owing to the overexp...
AbstractGrowth inhibition in the central nervous system (CNS) is a major barrier to axon regeneratio...
<p>Behavioral studies (Pinprick test) showing the effects of GD1a/GT1b-2b mAb and sham Abs on sensor...