<p>(a) Kernel density estimates of the risk scores predicted using models on UK2 and tested in the combined dataset Finn+NL+IT, for cases and controls. (b) Thresholds for risk scores in terms of population percent, with the top more likely to be a CD and the bottom more likely to be non-CD.</p
<p>Observed and expected distributions for the P values of linear trend for 3,985 tag-SNPs in 230 ge...
<p>Abbreviations: BMI, body mass index; CI, confidence interval; OR, odds ratio.</p><p><sup>a</sup> ...
<p>The number of non-CD cases “misdiagnosed” (wrongly implicated by GRS) per true CD cases “diagnose...
<p>Distribution of the seven SNPs-based genetic risk score in 1,387 NPC cases (black bars) and 1,459...
<p>Total genetic risk score averages and standard deviations were calculated for the 629 Amish LOAD ...
<p>AMD cases are shown in red, controls in blue, while overlapping bars are shaded blue/red. (<b>A</...
<p><i>1</i>: P values derived from the chi-square test of allele frequency.</p><p><i>2</i>: P values...
<p>F—frequency of the risk-associated allele. Area under each curve equals 1. Black line shows the d...
<p>Distributions of genetic risk scores among 1001 BARCOS individuals (<b>A</b>) and 11 HBM probands...
<p>Distribution of risk allele frequencies in type 2 diabetic cases and controls.</p
<p>The odds ratios for MS are shown according to the number of risk alleles carried. The reference v...
<p>*The number represents the numbers of risk genotypes.</p>†<p>Two-sided χ<sup>2</sup> test for the...
Distribution of predicted risks for all-cause mortality in the test cohort (n = 125,657).</p
<p>A high T2D Genetic Risk Score (GRS) had been previously shown to significantly associate with inc...
Polygenic risk scores are gaining more and more attention for estimating genetic risks for liabiliti...
<p>Observed and expected distributions for the P values of linear trend for 3,985 tag-SNPs in 230 ge...
<p>Abbreviations: BMI, body mass index; CI, confidence interval; OR, odds ratio.</p><p><sup>a</sup> ...
<p>The number of non-CD cases “misdiagnosed” (wrongly implicated by GRS) per true CD cases “diagnose...
<p>Distribution of the seven SNPs-based genetic risk score in 1,387 NPC cases (black bars) and 1,459...
<p>Total genetic risk score averages and standard deviations were calculated for the 629 Amish LOAD ...
<p>AMD cases are shown in red, controls in blue, while overlapping bars are shaded blue/red. (<b>A</...
<p><i>1</i>: P values derived from the chi-square test of allele frequency.</p><p><i>2</i>: P values...
<p>F—frequency of the risk-associated allele. Area under each curve equals 1. Black line shows the d...
<p>Distributions of genetic risk scores among 1001 BARCOS individuals (<b>A</b>) and 11 HBM probands...
<p>Distribution of risk allele frequencies in type 2 diabetic cases and controls.</p
<p>The odds ratios for MS are shown according to the number of risk alleles carried. The reference v...
<p>*The number represents the numbers of risk genotypes.</p>†<p>Two-sided χ<sup>2</sup> test for the...
Distribution of predicted risks for all-cause mortality in the test cohort (n = 125,657).</p
<p>A high T2D Genetic Risk Score (GRS) had been previously shown to significantly associate with inc...
Polygenic risk scores are gaining more and more attention for estimating genetic risks for liabiliti...
<p>Observed and expected distributions for the P values of linear trend for 3,985 tag-SNPs in 230 ge...
<p>Abbreviations: BMI, body mass index; CI, confidence interval; OR, odds ratio.</p><p><sup>a</sup> ...
<p>The number of non-CD cases “misdiagnosed” (wrongly implicated by GRS) per true CD cases “diagnose...