Restored expression of KLF4 by 5-Aza inhibits the proliferation of cervical cancer cells.

<p>(A and B) KLF4 protein expression gradually increased in response to different doses of 5-Aza in SiHa and C33A cells, as detected by ICC. (C and D) The proliferation of SiHa (C) and C33A (D) cells treated with different doses of 5-Aza was determined by counting cells longitudinally. (E and F) The viability of SiHa and C33A cells treated with 10 mM 5-Aza was determined by the MTT assay. (G and H) The cell survival rate of cervical cancer cell lines SiHa and C33A treated by chemistry agent cisplatin was detected by the MTT assay. Bars indicate SE. *, P<0.05.