<p>Mainly adopted from Orozovic et al. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089306#pone.0089306-Orozovic1" target="_blank">[26]</a>.</p>1)<p>Sum of all R118K mutations.</p>2)<p>Mutation unrelated to inhibitor resistance.</p>3)<p>Isolates that were not analyzed.</p>4)<p>Previously published values.</p
Prevalence of mutations identified in clusters by phylogenetic analysis of 251 sequences with drug r...
Black dots: number of NS mutation per kb retrieved from each of the 32 variants sequenced. a, b and ...
<p>The frequencies of each specific mutation at codon 12 of K-RAS in not acceptable (<i>NA</i>) or a...
<p><b>A</b> Proportion of resistance mutations in first Prot/RT sequence from treatment naïve patien...
<p>Results for all INH-resistant strains are grouped, as well as the results for are wildtype strain...
<p>*HGMD Access code.</p><p><sup>#</sup>Variant Classification according to the ACMG and AMP guideli...
<p><b><u>Abbreviations:</u></b> Pos – amino acid position; AA – amino acid difference from consensus...
<p><b><u>Abbreviations:</u></b> Pos – amino acid position; AA – amino acid difference from consensus...
<p>Acceptable (<i>A</i>) and not acceptable (<i>NA</i>) tumor specimens with mutated (MUT) or wild-t...
<p><sup>a</sup> The listed resistant strain was mated with the isogenic sensitive strain of the oppo...
<p>Mutations in nuclear DNA from the 28 adapted strains from two lineages contained indels, SNPs and...
<p>The number of mutations occurring in <i>mucA</i> (blue bars), <i>lasR</i> (green bars) and <i>mex...
<p>Percentages are the proportion of tumors having a mutation within a subtype, e.g. 37% of Bronchio...
<p>250 samples from 234 drug-naive patients and 115 samples from 78 treated A/AE patients were genot...
1<p>Number of reads at which variant allele was called out of total number of reads at that position...
Prevalence of mutations identified in clusters by phylogenetic analysis of 251 sequences with drug r...
Black dots: number of NS mutation per kb retrieved from each of the 32 variants sequenced. a, b and ...
<p>The frequencies of each specific mutation at codon 12 of K-RAS in not acceptable (<i>NA</i>) or a...
<p><b>A</b> Proportion of resistance mutations in first Prot/RT sequence from treatment naïve patien...
<p>Results for all INH-resistant strains are grouped, as well as the results for are wildtype strain...
<p>*HGMD Access code.</p><p><sup>#</sup>Variant Classification according to the ACMG and AMP guideli...
<p><b><u>Abbreviations:</u></b> Pos – amino acid position; AA – amino acid difference from consensus...
<p><b><u>Abbreviations:</u></b> Pos – amino acid position; AA – amino acid difference from consensus...
<p>Acceptable (<i>A</i>) and not acceptable (<i>NA</i>) tumor specimens with mutated (MUT) or wild-t...
<p><sup>a</sup> The listed resistant strain was mated with the isogenic sensitive strain of the oppo...
<p>Mutations in nuclear DNA from the 28 adapted strains from two lineages contained indels, SNPs and...
<p>The number of mutations occurring in <i>mucA</i> (blue bars), <i>lasR</i> (green bars) and <i>mex...
<p>Percentages are the proportion of tumors having a mutation within a subtype, e.g. 37% of Bronchio...
<p>250 samples from 234 drug-naive patients and 115 samples from 78 treated A/AE patients were genot...
1<p>Number of reads at which variant allele was called out of total number of reads at that position...
Prevalence of mutations identified in clusters by phylogenetic analysis of 251 sequences with drug r...
Black dots: number of NS mutation per kb retrieved from each of the 32 variants sequenced. a, b and ...
<p>The frequencies of each specific mutation at codon 12 of K-RAS in not acceptable (<i>NA</i>) or a...