Proportion of CKD patients (N = 1,989) who received ≥ 1 prescription of CND, stratified by classes.

<p>Proportion of CKD patients (N = 1,989) who received at least one prescription of contraindicated nephrotoxic drugs, stratified by drug classes, within one year prior or after first CKD diagnosis, and within one year after the entry in dialysis (N = 112) within one year prior or after first CKD diagnosis, and within one year after the entry in dialysis (N = 112). Others: zoledronate, lithium, antineoplastic agents (methotrexate, interferon alfa-2B), gold preparations (auranofin), hydrochlorothiazide. Low dosage acetylsalicylic acid was not included among NSAIDs, but it was analysed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089072#pone-0089072-g005" target="_blank">Figure 5</a>, separately. CND: contraindicated nephrotoxic drug.