Effect of ILT7 cross-linking on T cell activation in a pDC-T cell co-culture system.

<p>Flow cytometry dot plots (<b>A</b> and <b>C</b>) showing the expression of CD38 and CD69 in relation to violet proliferation dye (VPD) dilution in CD8 T cells (<b>A</b>) and CD4 T cells (<b>C</b>) co-cultured with autologous pDC (1∶10), in presence of different combinations of TLR9L (CpG), XL-ILT7 and staphyloccoccal enterotoxin B (SEB). One representative example of experiments performed on N = 3 independent donors is shown. Summary of results obtained in N = 3 independent experiments for CD38 expression, CD69 expression and proliferations (%VPDlow) in CD8 (<b>B</b>) and CD4 (<b>D</b>) T cells in pDC-T cell cocultures in presence of different combinations of TLR9L (CpG), XL-ILT7 and SEB. In <b>B</b> and <b>D</b>, dots indicate individual experiments.