Effect of ILT7 cross-linking on TLR7/9-induced expression of activation and costimulatory markers by pDC.

<p>Frequency of CD83+, CD80+, CD40+ and CD86+ pDC (<b>A</b>) and MFI of CD83, CD80, CD40 and CD86 on pDC (<b>B</b>) in PBMC stimulated with TLR7L or TLR9L in the absence (isotype control) or presence of XL-ILT7. In each plot, dots indicate individual experiments and crosses indicate medians for each condition. Numbers above brackets indicate P values for pair wise comparisons (Wilcoxon sign rank test).