Cardiomyocyte nuclear morphology is altered in response to loss of Nesprin 1 and/or 2.

<p>(A) Representative 40× images of isolated cardiomyocytes (Blue = DAPI, Green = Phalloidin). White bar = 15 µm. (B–G) Morphological analyses of cardiomyocytes examining (B) Myocyte area (C) Nuclear circularity (D) Nuclear area (E) Nuclear perimeter (F) Nuclear length or (G) Nuclear distance. N = 200–300 cells per condition, from 3–4 mice. ANOVA with a post hoc Bonferroni test *p<0.05, #p<0.01.