<p>The first order sensitivity index of the cellular model’s parameters for (A,B) the -, (C,D) the receptors, (E,F) the - internalized and (G) active - in the diffusive region. On the left column the phenotype and on the right column with exception of the - in the diffusive region (G) which is independent of the phenotype.</p
Local sensitivity analysis was performed by examining the sensitivity of model outputs to small chan...
The model incorporates the formation of receptor-ligand complex from extracellular IL-2 and receptor...
<p>Sensitivity of (maximal extracellular in the input zone) to variation in selected model paramet...
<p>The first order sensitivity index of the tissue model’s parameters for the tissue sub-population:...
<p>The first order sensitivity indexes of the bone model’s parameters for (A) osteocytes, (B) osteoc...
<p>Cellular parameters for excitatory and inhibitory (including global) cells.</p
Biophysically detailed cardiac cell models are based upon stiff ordinary differential equations desc...
<p>The states dynamics is shown on line A; the sensitivity dynamics for gene X is shown on line B an...
<p>The horizontal axis indicates the log-transformed absolute value of sensitivity coefficients <i>S...
Sensitivity analysis was performed for the 39 parameters in the T cell model. The transition actions...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
Local sensitivity analysis was performed by examining the sensitivity of model outputs (total recept...
<p>Concentration-time profiles of LRS and LRI computed at two values of the endocytic downregulation...
The regulatory systems that allow cells to adapt to their environments are exceedingly complex, and ...
<p>(A) Model output of the % of initial free β-arrestin 2 through 40 min in CXCR4<sup>+</sup>, CXCR7...
Local sensitivity analysis was performed by examining the sensitivity of model outputs to small chan...
The model incorporates the formation of receptor-ligand complex from extracellular IL-2 and receptor...
<p>Sensitivity of (maximal extracellular in the input zone) to variation in selected model paramet...
<p>The first order sensitivity index of the tissue model’s parameters for the tissue sub-population:...
<p>The first order sensitivity indexes of the bone model’s parameters for (A) osteocytes, (B) osteoc...
<p>Cellular parameters for excitatory and inhibitory (including global) cells.</p
Biophysically detailed cardiac cell models are based upon stiff ordinary differential equations desc...
<p>The states dynamics is shown on line A; the sensitivity dynamics for gene X is shown on line B an...
<p>The horizontal axis indicates the log-transformed absolute value of sensitivity coefficients <i>S...
Sensitivity analysis was performed for the 39 parameters in the T cell model. The transition actions...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
Local sensitivity analysis was performed by examining the sensitivity of model outputs (total recept...
<p>Concentration-time profiles of LRS and LRI computed at two values of the endocytic downregulation...
The regulatory systems that allow cells to adapt to their environments are exceedingly complex, and ...
<p>(A) Model output of the % of initial free β-arrestin 2 through 40 min in CXCR4<sup>+</sup>, CXCR7...
Local sensitivity analysis was performed by examining the sensitivity of model outputs to small chan...
The model incorporates the formation of receptor-ligand complex from extracellular IL-2 and receptor...
<p>Sensitivity of (maximal extracellular in the input zone) to variation in selected model paramet...