Assessment of changes in cell proliferation and morphology in the FT of smokers.

<p>A) Frequency of Ki67 positive cells in the FT of non-smokers (clear bars: n = 11) and smokers (filled bars: n = 10). B) Relative expression of Cyclin D1 transcripts within the FT of smokers and non smokers Expression of <i>CCND1</i> in the FT of smokers and non smokers. C) Histoscore analysis of the degree of ‘epithelial blebbing’ in non-smokers compared to smokers. Observed differences are significant at * <i>P</i><0.05. Gene expression was related to a <i>G6PDH</i> internal control.