Effects of RU486 and ML7 on MS-induced increase of IP to FD4 in PDN10 rats.

<p>Treatment with (A) ML7 (1 mg/kg/d in 0.9% NaCl i.p. at 24, 12 and 1 h before IP measurement), and (B) the GR antagonist RU486 (2 mg/kg/d in olive oil s.c. at 12 and 1 h before IP measurement) prior to MS prevented the IP increase in response to MS. Values are mean±SEM (n = 7–17 and n = 3–7 pups per group for experiment A and B respectively), and *P<0.05 **P<0.01, ***P<0.001 compared to their respective controls.