After 8 wks of feeding respective diets, energy expenditure (A), physical activity (B) and respiratory exchange ratio (RER) (C) were measured by indirect calorimetry.

<p>Gray bars represent night periods in A. Insulin sensitivity was assessed by an insulin tolerance test after 8 wks on respective diets and is shown as the average blood glucose levels before, and at 15, 30, 60 and 120 mins after injection of insulin (<b>D</b>) and as the average area under the curve (AUC) for each treatment group (<b>E</b>). (<b>F</b>) Fasting blood glucose levels are also reported. All values are shown as the mean ± SEM. Significant differences between groups are denoted by differing superscripts.