Regenerating gene-1(<i>Reg1</i>) and <i>Reg3β</i> gene expression in the pancreas of 4-month-old Wistar (□) and GK (▪) rats.

<p>Values are means ± SEM of three distinct experiments measured by quantitative RT-PCR for: A) islet-depleted exocrine-to-endocrine (isolated islets) tissue ratio; B) isolated islets: mRNA levels were expressed as the fold change in GK <i>vs</i> corresponding Wistar group. Glyceraldehyde-3-phosphate dehydrogenase was used as housekeeping gene. Three different islet isolations for each group of rats, * <i>p</i><0.05 and ** <i>p</i><0.01 <i>vs</i> Wistar rats, as analyzed by Student’s <i>t</i> test for unpaired data.