<p>Proteins significantly increased (positive fold change) and decreased (negative fold change) in older Tg-SwDI mice (9 months) relative to young Tg-SwDI mice (3 months).</p
(A) Increased body weight in female mice MARCH1-deficient mice (KO) compared to wildtype mice (WT) o...
(A) Study design. Animals were maintained on the 12% protein diet and dosed with vehicle or mLB-001 ...
*<p><i>P</i><0.05;</p>**<p><i>P</i><0.01;</p>***<p><i>P</i><0.001;</p><p>Pooled data from 9–18 month...
<p>Proteins significantly increased in older wild-type mice (9 months) relative to young wild-type m...
<p>A and B: TH<sup>+</sup> neurons were increased in glomerular layer of OB in tg mice (n = 4) at 10...
<p><b>A</b> Representative Western blot (SDS) and analysis of levels of <b>B</b> 3R Tau, <b>C</b> To...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
<p>P: postnatal ages.–: smaller, =: equal, +: higher, na: non-available. MN: motoneurone, INT nb in ...
<p>Similar expression patterns of BMP2, BMP4, TGF-β2, VEGF, and PDGF were observed between the two g...
<p>(A) Expression of mitochondrial genes was analyzed by RT-qPCR normalized to <i>Gapdh</i> and pres...
<p>Western blots showing protein expression of eEF1A2 and GAPDH (as a loading control) of animals fr...
<p>(A) p43−/− mice have a lower weight than wild-type mice. Age-dependent changes in body weight in ...
<p>*Gene expression microarray data were expressed as fold changes in MPS IIIB mice, relative to wt....
<p><b><i>A</i></b>, Blood glucose in 2-, 4- and 6-mo-old wild-type (WT) and IDE-KO (KO) mice followi...
<p>(A) Representative protein array images displayed the serum cytokine profiles in WT (left) and DJ...
(A) Increased body weight in female mice MARCH1-deficient mice (KO) compared to wildtype mice (WT) o...
(A) Study design. Animals were maintained on the 12% protein diet and dosed with vehicle or mLB-001 ...
*<p><i>P</i><0.05;</p>**<p><i>P</i><0.01;</p>***<p><i>P</i><0.001;</p><p>Pooled data from 9–18 month...
<p>Proteins significantly increased in older wild-type mice (9 months) relative to young wild-type m...
<p>A and B: TH<sup>+</sup> neurons were increased in glomerular layer of OB in tg mice (n = 4) at 10...
<p><b>A</b> Representative Western blot (SDS) and analysis of levels of <b>B</b> 3R Tau, <b>C</b> To...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
<p>P: postnatal ages.–: smaller, =: equal, +: higher, na: non-available. MN: motoneurone, INT nb in ...
<p>Similar expression patterns of BMP2, BMP4, TGF-β2, VEGF, and PDGF were observed between the two g...
<p>(A) Expression of mitochondrial genes was analyzed by RT-qPCR normalized to <i>Gapdh</i> and pres...
<p>Western blots showing protein expression of eEF1A2 and GAPDH (as a loading control) of animals fr...
<p>(A) p43−/− mice have a lower weight than wild-type mice. Age-dependent changes in body weight in ...
<p>*Gene expression microarray data were expressed as fold changes in MPS IIIB mice, relative to wt....
<p><b><i>A</i></b>, Blood glucose in 2-, 4- and 6-mo-old wild-type (WT) and IDE-KO (KO) mice followi...
<p>(A) Representative protein array images displayed the serum cytokine profiles in WT (left) and DJ...
(A) Increased body weight in female mice MARCH1-deficient mice (KO) compared to wildtype mice (WT) o...
(A) Study design. Animals were maintained on the 12% protein diet and dosed with vehicle or mLB-001 ...
*<p><i>P</i><0.05;</p>**<p><i>P</i><0.01;</p>***<p><i>P</i><0.001;</p><p>Pooled data from 9–18 month...