<p>Proteins significantly increased in older wild-type mice (9 months) relative to young wild-type mice (3 months).</p
<p><b><i>A</i></b>, Blood glucose in 2-, 4- and 6-mo-old wild-type (WT) and IDE-KO (KO) mice followi...
<p>Protein content of GLUT4 (A), HK2 (B), TBC1D1(C), TBC1D4 (D), Akt2 (E) and TRB-3 (F) was measured...
<p>Western immunoblots showing tau accumulation with age as quantified in the TBS-soluble (soluble p...
<p>Proteins significantly increased (positive fold change) and decreased (negative fold change) in o...
<p>(A) p43−/− mice have a lower weight than wild-type mice. Age-dependent changes in body weight in ...
<p>Western blots showing protein expression of eEF1A2 and GAPDH (as a loading control) of animals fr...
<p>(A) Expression of mitochondrial genes was analyzed by RT-qPCR normalized to <i>Gapdh</i> and pres...
<p><b>A</b> Representative Western blot (SDS) and analysis of levels of <b>B</b> 3R Tau, <b>C</b> To...
<p>A: Phenotypes of female Fzt:DU and DU6P mice at the age of 11, 29 and 42 weeks. B: Success for th...
<p>A and B: TH<sup>+</sup> neurons were increased in glomerular layer of OB in tg mice (n = 4) at 10...
(A) Study design. Animals were maintained on the 12% protein diet and dosed with vehicle or mLB-001 ...
<p>Grip strength (mean ± SEM) of wild type, heterozygous and homozygous mice as a function of age du...
<p>(A) Young mice (4 weeks old) and (B) wild-type old mice (84 weeks old). The green stars represent...
<p>Body weight (mean ± SEM) of wild type, heterozygous and homozygous mice as a function of age for ...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
<p><b><i>A</i></b>, Blood glucose in 2-, 4- and 6-mo-old wild-type (WT) and IDE-KO (KO) mice followi...
<p>Protein content of GLUT4 (A), HK2 (B), TBC1D1(C), TBC1D4 (D), Akt2 (E) and TRB-3 (F) was measured...
<p>Western immunoblots showing tau accumulation with age as quantified in the TBS-soluble (soluble p...
<p>Proteins significantly increased (positive fold change) and decreased (negative fold change) in o...
<p>(A) p43−/− mice have a lower weight than wild-type mice. Age-dependent changes in body weight in ...
<p>Western blots showing protein expression of eEF1A2 and GAPDH (as a loading control) of animals fr...
<p>(A) Expression of mitochondrial genes was analyzed by RT-qPCR normalized to <i>Gapdh</i> and pres...
<p><b>A</b> Representative Western blot (SDS) and analysis of levels of <b>B</b> 3R Tau, <b>C</b> To...
<p>A: Phenotypes of female Fzt:DU and DU6P mice at the age of 11, 29 and 42 weeks. B: Success for th...
<p>A and B: TH<sup>+</sup> neurons were increased in glomerular layer of OB in tg mice (n = 4) at 10...
(A) Study design. Animals were maintained on the 12% protein diet and dosed with vehicle or mLB-001 ...
<p>Grip strength (mean ± SEM) of wild type, heterozygous and homozygous mice as a function of age du...
<p>(A) Young mice (4 weeks old) and (B) wild-type old mice (84 weeks old). The green stars represent...
<p>Body weight (mean ± SEM) of wild type, heterozygous and homozygous mice as a function of age for ...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
<p><b><i>A</i></b>, Blood glucose in 2-, 4- and 6-mo-old wild-type (WT) and IDE-KO (KO) mice followi...
<p>Protein content of GLUT4 (A), HK2 (B), TBC1D1(C), TBC1D4 (D), Akt2 (E) and TRB-3 (F) was measured...
<p>Western immunoblots showing tau accumulation with age as quantified in the TBS-soluble (soluble p...