Luteoloside suppresses the NLRP3 inflammasome activation.
- Shao-hua Fan (527624)
- Yan-yan Wang (333583)
- Jun Lu (36049)
- Yuan-lin Zheng (527625)
- Dong-mei Wu (5658007)
- Meng-qiu Li (527626)
- Bin Hu (122268)
- Zi-feng Zhang (5658010)
- Wei Cheng (52808)
- Qun Shan (527627)
Publication date
February 2014
DOIAbstract
<p>(A) Western blot analyses of NLRP3, Caspase-1 (p10) and IL-1β protein expression in Huh-7 and SMMC-7721 cells exposed two different concentrations of luteoloside for 48 h. (B–D) Relative quantitation of NLRP3, Caspase-1 (p10) and IL-1β. (E) A hypothetical cascade pathway of NLRP3 inflammasome suppressed by luteoloside. *, <i>P</i><0.05; **, <i>P</i><0.01; ***, <i>P</i><0.001, versus non-luteoloside-treated control group.</p
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