B20-4.1.1 and K(1-3) Inhibit Spinal Cord Angiogenesis During EAE.

<p>Left sided panels show vessel counts as a function of disease duration. Filled circles indicate data for untreated EAE, open circles for EAE treated with B20-4.1.1 (upper left) or K(1-3) (lower left). Data are shown as mean ± SEM obtained from per mouse values from 6-8 mice. Significance is relative to control or between points linked by cross bars (*, ***; P<0.05, 0.001). Right sided images show CD31 positive vessels in spinal cord for indicated groups. Arrows point to examples of individual blood vessels. Scale bar = 50 µm.