<i>Slc7a5</i> gene expression and SLC7A5 transport activity in MS-<i>Slc7a5</i>-KO mouse muscles and impact on tissue growth.
- Nadège Poncet (527942)
- Fiona E. Mitchell (527943)
- Adel F. M. Ibrahim (188343)
- Victoria A. McGuire (527944)
- Grant English (527945)
- J. Simon C Arthur (527946)
- Yun-Bo Shi (193634)
- Peter M. Taylor (527947)
Publication date
February 2014
DOIAbstract
<p>(A) Reduced expression of Slc7a5 mRNA in MS-<i>Slc7a5</i>-KO mouse gastrocnemius muscle (n = 24) compared to wild-type (n = 36). ***indicates p<0.001 by unpaired t-test. (B) Reduced SLC7A5 (System L1) transport function (measured as Phe uptake) in MS-<i>Slc7a5</i>-KO soleus muscle (n = 4) compared to wild-type (n = 6) *indicates p<0.05 by unpaired t-test. (C) No difference on the growth rate of MS-<i>Slc7a5</i>-KO and wild-type mice on standard chow diet (14% protein) (n = 5).</p
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