Effects of CMV and age on the proportion of CD28-CD8+ T cells expressing CD57.

<p>The proportion of CD28- and CD28-CD57+ CD8+ T cells (<b>A</b>), of CD28-CD8+ T cells expressing CD57 (<b>B</b>), and of maturational subsets of CD28- CD8+ T cells: transitional memory, T_TR, (CD28-CD27+CCR7-CD45RA-) and terminally differentiated, T_TEMRA, (CD28-CD27-CCR7-CD45RA+) CD8+ T cells (<b>C</b>), were compared between HIV-uninfected asymptomatic CMV-seronegative (green) and CMV-seropositive (blue) participants. Bars represent median values. The correlation between the proportion of CD28-CD8+ T cells expressing CD57 and age was also assessed among CMV-seropositive HIV-uninfected adults (<b>D</b>). The red line represents a linear prediction.