<p>The examples in the table are selected based on that the genes have a mutant frequency greater than 40 in the COSMIC database to show the estimation for the common cases. Due to the limited space, the prediction for the samples with more than 3 mutant cancer genes is not shown. Refer to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089244#pone.0089244.s003" target="_blank">Table S3</a> for a complete result.</p><p>The random chance is 1/<i>n!</i>, where <i>n</i> is the number of mutant cancer genes in the sample.</p><p>Note, any two samples with the same set of mutant genes have identical predicted results.</p
The temporal order of cancer gene mutations in tumors is essential for understanding and treating th...
<p>A: the number of sequences that drove the cancerous state.</p><p>B: the number of sequences that ...
In this paper we discuss some natural limitations in quantitative inference about the frequency, cor...
<p>For each human gene, the expected number of mutations is obtained based on the normal mutation pa...
<p>Percent: the sum of the probabilities of the orders initiated by the gene versus the total of the...
Abstract Background Because driver mutations provide ...
<div><p>One of the goals of cancer research is to identify a set of genes that cause or control dise...
<p>Assumptions as to the number of symmetric (<i>n</i><sub>1</sub>) and asymmetric cell divisions (<...
<p>(<b>a</b>) The occurrence and co-occurrence frequencies of the cancer gene mutations and are de...
Although the role of evolutionary process in cancer progression is widely accepted, increasing atten...
<p>Percentages are the proportion of tumors having a mutation within a subtype, e.g. 37% of Bronchio...
<div><p>The temporal order of cancer gene mutations in tumors is essential for understanding and tre...
International audienceHumans have invested several genes in DNA repair and fidelity replication. To ...
Many biomedical problems relate to mutant functional properties across a sequence space of interest,...
The temporal order of cancer gene mutations in tumors is essential for understanding and treating th...
The temporal order of cancer gene mutations in tumors is essential for understanding and treating th...
<p>A: the number of sequences that drove the cancerous state.</p><p>B: the number of sequences that ...
In this paper we discuss some natural limitations in quantitative inference about the frequency, cor...
<p>For each human gene, the expected number of mutations is obtained based on the normal mutation pa...
<p>Percent: the sum of the probabilities of the orders initiated by the gene versus the total of the...
Abstract Background Because driver mutations provide ...
<div><p>One of the goals of cancer research is to identify a set of genes that cause or control dise...
<p>Assumptions as to the number of symmetric (<i>n</i><sub>1</sub>) and asymmetric cell divisions (<...
<p>(<b>a</b>) The occurrence and co-occurrence frequencies of the cancer gene mutations and are de...
Although the role of evolutionary process in cancer progression is widely accepted, increasing atten...
<p>Percentages are the proportion of tumors having a mutation within a subtype, e.g. 37% of Bronchio...
<div><p>The temporal order of cancer gene mutations in tumors is essential for understanding and tre...
International audienceHumans have invested several genes in DNA repair and fidelity replication. To ...
Many biomedical problems relate to mutant functional properties across a sequence space of interest,...
The temporal order of cancer gene mutations in tumors is essential for understanding and treating th...
The temporal order of cancer gene mutations in tumors is essential for understanding and treating th...
<p>A: the number of sequences that drove the cancerous state.</p><p>B: the number of sequences that ...
In this paper we discuss some natural limitations in quantitative inference about the frequency, cor...