<p>Liver fibrosis was assessed by morphometric (A) and biochemical (B) measurement of hepatic collagen (Hyp) contents. Hepatic inflammation was measured by serum ALT activities (C). Sirius red staining of hepatic collagen showed circumferential fibrosis in C57BL/6J mice (D) and pronounced fibrosis in DBA/2J mice (E), corresponding to mean F-scores of 2.0±0.1 and 3.9±0.1, respectively.</p
<p>Mice were CCl<sub>4</sub> treated twice a week for a total period of 4 weeks. After the second we...
<p>Acute liver injury after CCl<sub>4</sub> challenge is associated with augmented hepatic expressio...
<p>C57/BL/6 mice were given CCl<sub>4</sub> for 6 weeks and then remained untreated for 7 additional...
<p>Liver fibrosis was induced by intraperitoneal injection of CCl<sub>4</sub> twice a week for 3 wee...
<p><b>(A)</b> Regimen of liver fibrosis induction (sacrificed after 4-weeks (intermediate fibrosis) ...
<p>Male C57BL/6J WT mice (n = 4) and IDO-KO mice (n = 5) were treated with CCl<sub>4</sub> (1 mL/kg,...
<p>(A) Example of histological changes in CCl4-treated mice along the 16 weeks of study. Hepatic sec...
<p>CCl<sub>4</sub> was given to C57/BL/6 mice for 6 weeks as detailed in Methods. <b>(A)</b> Sirius ...
<p>Livers were obtained from WT, NOX1KO, and NOX4KO mice by 12 intragastric administrations with CCl...
<p>Mice were injected with olive oil or CCl<sub>4</sub> twice weekly for 4 weeks and collagen was de...
<p>(A) Liver tissues from sham-operated controls did not show any hepatic inflammation or bile duct ...
<p>(A) CCl<sub>4</sub> injection promotes collagen deposition. Masson's trichrome staining was used ...
<p>The CCl<sub>4</sub> fibrosis model was induced for 4 weeks in WT (horizontal gradient bars) and T...
<p>C57BL/6J mice were allowed free access to 2% (vol/vol) ethanol diet or pair-fed control diet and ...
<p>CCL3 expression is increased in MCD-fed wild-type mice compared to untreated control (<b>A</b>). ...
<p>Mice were CCl<sub>4</sub> treated twice a week for a total period of 4 weeks. After the second we...
<p>Acute liver injury after CCl<sub>4</sub> challenge is associated with augmented hepatic expressio...
<p>C57/BL/6 mice were given CCl<sub>4</sub> for 6 weeks and then remained untreated for 7 additional...
<p>Liver fibrosis was induced by intraperitoneal injection of CCl<sub>4</sub> twice a week for 3 wee...
<p><b>(A)</b> Regimen of liver fibrosis induction (sacrificed after 4-weeks (intermediate fibrosis) ...
<p>Male C57BL/6J WT mice (n = 4) and IDO-KO mice (n = 5) were treated with CCl<sub>4</sub> (1 mL/kg,...
<p>(A) Example of histological changes in CCl4-treated mice along the 16 weeks of study. Hepatic sec...
<p>CCl<sub>4</sub> was given to C57/BL/6 mice for 6 weeks as detailed in Methods. <b>(A)</b> Sirius ...
<p>Livers were obtained from WT, NOX1KO, and NOX4KO mice by 12 intragastric administrations with CCl...
<p>Mice were injected with olive oil or CCl<sub>4</sub> twice weekly for 4 weeks and collagen was de...
<p>(A) Liver tissues from sham-operated controls did not show any hepatic inflammation or bile duct ...
<p>(A) CCl<sub>4</sub> injection promotes collagen deposition. Masson's trichrome staining was used ...
<p>The CCl<sub>4</sub> fibrosis model was induced for 4 weeks in WT (horizontal gradient bars) and T...
<p>C57BL/6J mice were allowed free access to 2% (vol/vol) ethanol diet or pair-fed control diet and ...
<p>CCL3 expression is increased in MCD-fed wild-type mice compared to untreated control (<b>A</b>). ...
<p>Mice were CCl<sub>4</sub> treated twice a week for a total period of 4 weeks. After the second we...
<p>Acute liver injury after CCl<sub>4</sub> challenge is associated with augmented hepatic expressio...
<p>C57/BL/6 mice were given CCl<sub>4</sub> for 6 weeks and then remained untreated for 7 additional...