Extracellular recordings of paced cellular preparations generated from MEAs.

<p>(A) The MEA plate consists of 60 titanium nitride (TiN) electrodes. Each electrode has a diameter of 30 µM and the interelectrode distance from centre to centre is 200 µM. (B) Cells were seeded as confluent drop directly on the TiN electrodes. (C) Representative extracellular field potentials after line stimulation are shown in. (D) CV are calculated as a time delay between the artefact of stimulation and the resulting field potential against the respective distance of the electrodes from the origin of excitation in clones 2, 3 and 6 (E).