MiR-30c regulates cell proliferation, migration and invasion in EC.

<p>(A). A MTT assay shows that miR-30c mimics suppressed cell viability (upper), whereas miR-30c inhibitor promoted cell viability (lower). (B). MiR-30c-mimics reduces relative cell proliferation (upper), whereas miR-30c-inhibitor increases relative cell proliferation (lower), respectively at 72 and 96 h after transfection. (C). Representative photographs of the wound-healing assay showing the migratory ability of the transfected cells at 0, 24 and 48 h after wounding. (D). Representative photographs of cell invasion in a transwell assay. The average number of cells was counted from 5 random microscopic fields (×200). The values shown are the mean values ± SD of relative cell invasion. (*P<0.05, **P<0.01).