Hypothetical model of the mode of action of açaí aqueous extract (AAE) on <i>C. elegans</i>.
- Larissa de Freitas Bonomo (529976)
- David Nunes Silva (529977)
- Patrícia Ferreira Boasquivis (529978)
- Franciny Aparecida Paiva (529979)
- Joyce Ferreira da Costa Guerra (529980)
- Talita Alves Faria Martins (529981)
- Álvaro Gustavo de Jesus Torres (529982)
- Igor Thadeu Borges Raposo de Paula (529983)
- Washington Luiz Caneschi (529984)
- Philippe Jacolot (529985)
- Nicolas Grossin (529986)
- Frederic J. Tessier (529987)
- Eric Boulanger (529988)
- Marcelo Eustáquio Silva (529989)
- Maria Lúcia Pedrosa (529990)
- Riva de Paula Oliveira (529991)
Publication date
March 2014
DOIAbstract
<p>Text marked within a rectangle represents modulators or data observed experimentally in this manuscript. AAE modulates oxidative stress resistance by direct and indirect mechanisms. AAE removes ROS directly and prevents <i>gcs-1</i> activation and SH level reduction which in turn increases oxidative stress resistance. AAE also promotes oxidative stress resistance indirectly through DAF-16/OSR-1/UNC-43/SEK-1. In addition, AAE increases osmotic stress resistance, possibly as a result of impaired protein homeostasis and/or increased ionic strength.</p
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