<p>(A) Intraepithelial eosinophils (B) Inflammatory cells in the lamina propria of the trachea. OVA-exposed animals treated with vehicle alone are compared to unexposed animals or to animals treated with 4 or 20 mg/kg/day of ISU201, or of 1 mg/kg/day dexamethasone. Data are mean ± SEM (<i>n</i> = 6 samples per group). Significant differences relative to the naïve group are shown as **(p<0.01) and ***(p<0.001); relative to the vehicle-treated group are shown as #(p<0.05) and ##(p<0.01).</p
<p>Airway function was detected and BAL fluid and serum were collected and evaluated by ELISA. <b>A<...
Asthma is a chronic inflammatory disease of the airways. Using a murine model which replicates many ...
Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 92, Suppl. II, pp. 223-226 Role of eosinophilic airway i...
<p>(A) Subepithelial accumulation of collagen (B) Epithelial thickening (C) Mucous cell change. OVA-...
<p>(A) Photomicrograph of immunopositive nuclei (brown) in epithelial cells lining the trachea, orig...
<p>Results are expressed as mean ± SD (n = 7). NEU, neutrophils; LYMs, lymphocytes; EOSs, eosinophil...
Eosinophils play a central role in the establishment and outcome of bronchial inflammation in asthma...
Background: The aim of the study was to compare the influence of TNF antagonism and corticosteroid t...
<p>Mice were sensitised and challenged for six weeks with PBS or OVA (black bars). OVA treatment was...
<p><b>(A)</b>, Decreased infiltration of eosinophils in the BAL fluid of asthmatic SH-2251-administe...
<p>Treatment with ACA reduced (a) IL-13 expression and (b) almost completely blocked IL-4 expression...
<p>OVA induced the expression of Th1- and Th2-related cytokines. AO reduced the expression of Th1-re...
Asthma is the commonest treatable chronic pulmonary disease affecting all ages and affecting up to 2...
To elucidate the cause of severe asthma in adults, an animal model of chronic asthma was established...
The development of non-invasive methods to assess airway inflammation in asthma has made it possible...
<p>Airway function was detected and BAL fluid and serum were collected and evaluated by ELISA. <b>A<...
Asthma is a chronic inflammatory disease of the airways. Using a murine model which replicates many ...
Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 92, Suppl. II, pp. 223-226 Role of eosinophilic airway i...
<p>(A) Subepithelial accumulation of collagen (B) Epithelial thickening (C) Mucous cell change. OVA-...
<p>(A) Photomicrograph of immunopositive nuclei (brown) in epithelial cells lining the trachea, orig...
<p>Results are expressed as mean ± SD (n = 7). NEU, neutrophils; LYMs, lymphocytes; EOSs, eosinophil...
Eosinophils play a central role in the establishment and outcome of bronchial inflammation in asthma...
Background: The aim of the study was to compare the influence of TNF antagonism and corticosteroid t...
<p>Mice were sensitised and challenged for six weeks with PBS or OVA (black bars). OVA treatment was...
<p><b>(A)</b>, Decreased infiltration of eosinophils in the BAL fluid of asthmatic SH-2251-administe...
<p>Treatment with ACA reduced (a) IL-13 expression and (b) almost completely blocked IL-4 expression...
<p>OVA induced the expression of Th1- and Th2-related cytokines. AO reduced the expression of Th1-re...
Asthma is the commonest treatable chronic pulmonary disease affecting all ages and affecting up to 2...
To elucidate the cause of severe asthma in adults, an animal model of chronic asthma was established...
The development of non-invasive methods to assess airway inflammation in asthma has made it possible...
<p>Airway function was detected and BAL fluid and serum were collected and evaluated by ELISA. <b>A<...
Asthma is a chronic inflammatory disease of the airways. Using a murine model which replicates many ...
Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 92, Suppl. II, pp. 223-226 Role of eosinophilic airway i...