<p>Asterisks (*) symbolize significant difference (<i>p</i><0.05) in <i>in vitro</i> antitumour activity of <b>1</b>–<b>3</b> as compared to <i>cisplatin</i>.</p
a<p>Antiproliferative activity was measured using the WST-1 assay. Values are the average of two ind...
Ed by cell counts and was expressed as percent of control (untreated cells). Experiments were repeat...
Ed by cell counts and was expressed as percent of control (untreated cells). Experiments were repeat...
<p>Cells were treated with the tested compounds for 24 h; measurements were performed in triplicate,...
<p> <b><i>vitro</i></b><b> cytotoxicity against selected cancer cell lines for complexes 4–6 and </b...
<p>The data were obtained by the MTT assay against human lung carcinoma A549, cervix epithelial carc...
<p>The results of the <i>in vitro</i> antitumor activity testing of <b>1</b>–<b>6</b>, <i>cisplatin<...
<p>Cytotoxic activity of <b>2</b>–<b>5</b> at their 10 μM concentrations against the A2780 (top pane...
<p><b><i>A–D:</i></b> Paraffin-embedded UM-SCC-74A tumor samples were stained for pSTAT3 (Y705) and ...
<p>MTT assay was performed on human normal fibroblast cells treated with [(dmb)<sub>2</sub>Ru(obip)R...
<p>Animals bearing UM-SCC-74A, CAL27 and CAL27-CisR were treated with H-4073 (50 ppm) or cisplatin (...
<p>Results are expressed as mean ± SD of at least three independent experiments. IC<sub>50</sub> val...
<p><i>In vitro</i> antiproliferative potency (IC<sub>50</sub>-µM) of compounds <b>5a–r</b> and the s...
In order to compare the mechanistic properties of the antitumour-active trans platinum complex trans...
<p>IC30, 30% inhibitory concentration of cisplatin; IC50, 50% inhibitory concentration of cisplatin;...
a<p>Antiproliferative activity was measured using the WST-1 assay. Values are the average of two ind...
Ed by cell counts and was expressed as percent of control (untreated cells). Experiments were repeat...
Ed by cell counts and was expressed as percent of control (untreated cells). Experiments were repeat...
<p>Cells were treated with the tested compounds for 24 h; measurements were performed in triplicate,...
<p> <b><i>vitro</i></b><b> cytotoxicity against selected cancer cell lines for complexes 4–6 and </b...
<p>The data were obtained by the MTT assay against human lung carcinoma A549, cervix epithelial carc...
<p>The results of the <i>in vitro</i> antitumor activity testing of <b>1</b>–<b>6</b>, <i>cisplatin<...
<p>Cytotoxic activity of <b>2</b>–<b>5</b> at their 10 μM concentrations against the A2780 (top pane...
<p><b><i>A–D:</i></b> Paraffin-embedded UM-SCC-74A tumor samples were stained for pSTAT3 (Y705) and ...
<p>MTT assay was performed on human normal fibroblast cells treated with [(dmb)<sub>2</sub>Ru(obip)R...
<p>Animals bearing UM-SCC-74A, CAL27 and CAL27-CisR were treated with H-4073 (50 ppm) or cisplatin (...
<p>Results are expressed as mean ± SD of at least three independent experiments. IC<sub>50</sub> val...
<p><i>In vitro</i> antiproliferative potency (IC<sub>50</sub>-µM) of compounds <b>5a–r</b> and the s...
In order to compare the mechanistic properties of the antitumour-active trans platinum complex trans...
<p>IC30, 30% inhibitory concentration of cisplatin; IC50, 50% inhibitory concentration of cisplatin;...
a<p>Antiproliferative activity was measured using the WST-1 assay. Values are the average of two ind...
Ed by cell counts and was expressed as percent of control (untreated cells). Experiments were repeat...
Ed by cell counts and was expressed as percent of control (untreated cells). Experiments were repeat...