Effects of Gu-4 treatment on lung injury in rats with CLP-induced sepsis.

<p>Ten hours after CLP, lung tissues from sham control rats (A), saline treated CLP rats (B), Gu-4 treated CLP rats (C) and EP treated CLP rats (D) were collected and subjected to Hematoxylin and Eosin staining and examined by light microscopy (magnification, ×100). Histological scoring of lung injury were evaluated based on aspects of congestion, edema and inflammation E: The lung injury seriously induced by CLP was greatly attenuated by Gu-4 treatment. Data in E are expressed as mean ± S.D. (n = 5 rat/group) *, <i>p</i><0.05; **, <i>p</i><0.01.