<p>DMSO, the solvent of MEK inhibitor, was used as a control.</p><p>Cell counts and numbers of cell divisions are presented as mean ± s.e.m.</p><p>Conditions are highlighted in bold and italic letters when cell fate changes are expected.</p><p>Numbers of cell divisions are highlighted in bold and italic letters when a change in the number was observed.</p><p>Mch, mesenchyme. Mu, muscle.</p
<p>A) A dose response effect on muscle cell proliferation after 3 days upon MK-4 treatment, compared...
<p>P19 aggregates were treated with 1% DMSO to induce differentiation into mesoderm. Total mRNA was ...
Developmental series of DMSO controls and embryos treated with 50 μM of SMIFH2 at the beginning of c...
<p>(A) Muscle and mesenchyme blastomeres were isolated from 64-cell embryos treated with DMSO as a c...
<p>Embryos were treated with 10 µM, 25 µM or 50 µM of the MEK inhibitor U0126. Control groups were i...
DMSO is a commonly used solvent in biological studies, as it is an amphipathic molecule soluble in b...
<p>B7.3 and B7.7 mesenchyme blastomeres were isolated from 64-cell embryos that had been injected wi...
Human embryonic stem cells (hESCs) can be captured in a primed state in which they resemble the post...
<p>A) Immunofluorescence (IF) using anti-EYFP and anti-MyoD-specific antibodies on transverse sectio...
<p>(A) Schematic representation of arrested 110-cell embryos, showing the position of each tissue pr...
U0126-treated animals. As treated and wt animals could not be separated at this stage, a large numbe...
U0126-treated animals. As treated and wt animals could not be separated at this stage, a large numbe...
<p>(A). <i>Mixl1:GFP</i> ES cells were cultured as aggregates in MEDII for 3 days to form EPL cells....
<p>(<b>A</b>) Undifferentiated K5<sup>+</sup>K19<sup>-</sup> hMECs were starved of serum/growth fact...
<p>A) Numbers of mitotic cells scored in 19 embryos from HH4-10. For HH4-5 embryos, cells in the lat...
<p>A) A dose response effect on muscle cell proliferation after 3 days upon MK-4 treatment, compared...
<p>P19 aggregates were treated with 1% DMSO to induce differentiation into mesoderm. Total mRNA was ...
Developmental series of DMSO controls and embryos treated with 50 μM of SMIFH2 at the beginning of c...
<p>(A) Muscle and mesenchyme blastomeres were isolated from 64-cell embryos treated with DMSO as a c...
<p>Embryos were treated with 10 µM, 25 µM or 50 µM of the MEK inhibitor U0126. Control groups were i...
DMSO is a commonly used solvent in biological studies, as it is an amphipathic molecule soluble in b...
<p>B7.3 and B7.7 mesenchyme blastomeres were isolated from 64-cell embryos that had been injected wi...
Human embryonic stem cells (hESCs) can be captured in a primed state in which they resemble the post...
<p>A) Immunofluorescence (IF) using anti-EYFP and anti-MyoD-specific antibodies on transverse sectio...
<p>(A) Schematic representation of arrested 110-cell embryos, showing the position of each tissue pr...
U0126-treated animals. As treated and wt animals could not be separated at this stage, a large numbe...
U0126-treated animals. As treated and wt animals could not be separated at this stage, a large numbe...
<p>(A). <i>Mixl1:GFP</i> ES cells were cultured as aggregates in MEDII for 3 days to form EPL cells....
<p>(<b>A</b>) Undifferentiated K5<sup>+</sup>K19<sup>-</sup> hMECs were starved of serum/growth fact...
<p>A) Numbers of mitotic cells scored in 19 embryos from HH4-10. For HH4-5 embryos, cells in the lat...
<p>A) A dose response effect on muscle cell proliferation after 3 days upon MK-4 treatment, compared...
<p>P19 aggregates were treated with 1% DMSO to induce differentiation into mesoderm. Total mRNA was ...
Developmental series of DMSO controls and embryos treated with 50 μM of SMIFH2 at the beginning of c...