Glycoform ratios of PrP^res detected by Western blotting.

<p>PrP^res was detected with the Sha31 monoclonal antibody in the different BSE-derived prions propagated either in the natural hosts (A) or in transgenic mouse models over-expressing their corresponding PrP^C sequence (B). Atypical cattle-BSE H, sheep-scrapie, mouse-RML and human-sCJD isolates (C) are included for comparison purposes. Values are the normalized means from at least six repeated runs. Arrows indicate the reading direction of the axis.