Generation of CFTR<sup>−/−</sup> rats.
- Katherine L. Tuggle (532499)
- Susan E. Birket (276316)
- Xiaoxia Cui (532500)
- Jeong Hong (532501)
- Joe Warren (274996)
- Lara Reid (532502)
- Andre Chambers (532503)
- Diana Ji (532504)
- Kevin Gamber (532505)
- Kengyeh K. Chu (276310)
- Guillermo Tearney (532506)
- Li Ping Tang (154913)
- James A. Fortenberry (532507)
- Ming Du (532508)
- Joan M. Cadillac (532509)
- David M. Bedwell (401294)
- Steven M. Rowe (154935)
- Eric J. Sorscher (154931)
- Michelle V. Fanucchi (532510)
Publication date
March 2014
DOIAbstract
<p>(A) Animals at days 1 and 24 postnatal. (B) Results of PCR genotyping from a representative litter. (C) Western blot indicating expression of CFTR in wild-type rats and absence of CFTR protein from lungs of CFTR<sup>−/−</sup> animals. Arrow - CFTR. (D) Body weight values (mean ± SD) from wild-type and CFTR<sup>−/−</sup> rats from 12 to 44 days postnatal. (E) Survival curve for CFTR<sup>−/−</sup> rats from postnatal day 1 to 44 (p<0.05 for all groups, n = 12–67 animals/group).</p
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