Conservation of SUMOplot predicted tomosyn SUMOylation sites.

<p>Protein alignment of tomosyn isoforms in different species, as well as the homologous proteins Lgl and yeast Sro7 and Sro77. Lysine residues that are predicted to be subject to SUMOylation in mouse tomosyn are highlighted with black boxes. SUMOplot prediction scores for (A) tomosyn-m2 K279, (B) tomosyn-m1 K285, (C) tomosyn-m1 K298 / tomosyn-m2 K309 and (D) tomosyn m-1 K730 are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091697#pone-0091697-t001" target="_blank">table 1</a>. Colours represent amino acid physicochemical properties: small (red), acidic (blue), basic (magenta), hydroxyl/sulfhydryl/amine/G (green).